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Ready for No. 5 Xavier versus No. 1 Villanova?

This week's highest-profile Top 25 basketball game will unfold at 7 p.m. Wednesday at Cintas Center when No. 5 Xavier hosts No. 1 Villanova in a Big East showdown of epic proportions.

Xavier had a crack at Nova in its Big East opener on the Wildcats’ court and lost 95-64. The game was characterized by point guard Edmond Sumner’s hard fall and concussion several minutes into play.

The Musketeers never recovered.

Ryan Arcidiacono scored a season-high 27 points behind seven 3-pointers and Jay Wright’s team dictated an outing in which Xavier committed 19 turnovers.