Maddy Sissoko had 11 points and 10 rebounds for the Spartans (1-1), who began the season with a loss to James Madison in overtime before getting a lopsided win over an overmatched team in its second season of Division I basketball.
The Screaming Eagles (0-2) missed 17 of their first 18 shots and trailed 37-14 at halftime. They were much more competitive early in the second half, going on a 12-0 run to cut the deficit to 15 points.
Michigan State responded by making five of six shots to take a 22-point lead and coasted to a much-needed victory, less than a week before facing No.