The West Virginia Mountaineers and TCU Horned Frogs will forever be linked to the 2012 realignment that saw them jump from separate conferences to the Big 12. Since joining the conference, TCU is 74-51. TCU has enjoyed a bit more success than the Mountaineers, with three seasons in double digit wins. In 2014 the Horned Frogs shared the 2014 conference title and in 2017 played for a conference championship, but the Frogs have also experienced more lows than the Mountaineers, having four seasons where they finished below .500.
Entering 2022, the Frogs have Max Duggan back after he threw for over 2,000 yards last season.