West Ham captain Mark Noble will be assessed after he took a blow to his knee against Leicester.
Alvaro Arbeloa, Arthur Masuaku, Diafra Sakho and Gokhan Tore remain out.
Manchester United are without defender Eric Bailly, who is now on international duty with the Ivory Coast at the Africa Cup of Nations.
Manager Jose Mourinho says Michael Carrick and Wayne Rooney have a chance of being involved after missing the New Year's Eve win over Middlesbrough.
Rooney has been out with a thigh problem, while Carrick has been ill.
MOTD COMMENTATOR'S NOTES
Jonathan Pearce: "I was lucky enough to be commentating alongside Sir Trevor Brooking for West Ham's thrilling Upton Park finale win over Manchester United.