West Ham's Aaron Cresswell will return after he was suspended for the Europa League quarter-final win over Lyon.
Kurt Zouma sprained his ankle in the recent defeat by Brentford and could be out for the remainder of the season.
Burnley Under-23 coach Mike Jackson will be in temporary charge of the team in the wake of Sean Dyche's departure.
Defender Erik Pieters could return from a knee issue, while injured club captain Ben Mee will be on the touchline among the coaching staff.
LAWRO'S PREDICTION
I expected Burnley to kick on after beating Everton but to follow up a huge win like that by going to the bottom side and losing is a big set-back.