Captain Harry Kane and James Maddison both played for Tottenham as they lost 3-2 to West Ham in Ange Postecoglou's first match in charge.
Kane is in the final 12 months of his Tottenham contract and is a transfer target for German side Bayern Munich.
But 29-year-old Kane played the first half of the match in Perth, Australia, while Maddison made his debut following his £40m move from Leicester.
Danny Ings, Divin Mubama and Gianluca Scamacca scored West Ham's goals.
Australian Postecoglou won the Scottish Premiership in both his seasons at Celtic, also guiding the club to a domestic treble in 2022-23 before he became Spurs manager in June.