Senior officers have turned down a request from West Ham to police their stadium on matchdays - because the £700m ground does not have a "satisfactory" radio system.
The club requested a police presence in the ground after crowd trouble.
The Hammers only moved to the London Stadium at the start of the season.
"Until there is comprehensive radio coverage officers will not be routinely deployed within it," said the Metropolitan Police's Peter Terry.
Mr Terry, who is deputy assistant commissioner of the Metropolitan Police and in charge of specialist crime and operations, added: "The stadium operators are responsible for the safety and comfort of their customers and staff.