Nottingham Forest head coach Nuno Espirito Santo has said Africa Cup of Nations finalists Ola Aina, Willy Boly and Ibrahim Sangare will not be involved on Saturday.
Chris Wood and Gonzalo Montiel remain sidelined with hamstring injuries.
West Ham manager David Moyes will provide a squad fitness update later on Friday.
Lucas Paqueta has returned to training after a calf problem and could feature for the first time since early January.
MATCH FACTS
Head-to-head
- West Ham won the reverse fixture 3-2 in November and can beat Nottingham Forest home and away in a top-flight season for the first time since 1968-69.