Allan Saint-Maximin and Callum Wilson are likely to start for Newcastle following their game-changing impact as substitutes against Burnley.
West Ham manager David Moyes will provide an update on the fitness of his players on Friday.
Manuel Lanzini and Angelo Ogbonna could return but Aaron Cresswell and Mark Noble suffered injuries last weekend.
The Hammers are already without key pair Michail Antonio and Declan Rice.
LAWRO'S PREDICTION
Last weekend's win at Burnley was massive for Newcastle, who now have a bit of breathing space above the bottom three.
I'm going for a bit of an upset here, partly because I think Newcastle usually pick up points in bursts and also because they also have Allan Saint-Maximin and Callum Wilson to come into their starting XI after the impact they made off the bench against the Clarets.