Manchester United can make history by becoming just the third team in the history of top-flight English football to go an entire league campaign unbeaten away from home - if they avoid defeat at Wolves.
Elsewhere, Arsenal host Brighton with a spot in Europe still up for grabs and London rivals West Ham face Southampton.
Leeds are also still in contention for the Europa Conference League - they host West Brom - while Everton are at Manchester City, who will lift the Premier League trophy this afternoon.
Sportsmail's TOBY MILES will provide live coverage of the final day of the Premier League season, including all the build-up, team news and in-game updates from across the country.