David Moyes believes it would be "a great achievement" if West Ham could reach a European quarter-final for the second successive year.
The Hammers face AEK Larnaca in the first leg of their Europa Conference League last-16 tie on Thursday.
Last season they were knocked out in the semi-finals of the Europa League by Eintracht Frankfurt.
"We've got a job to do to try to reach the quarter-finals at the moment," said Moyes.
"It would be a great achievement if West Ham could talk about being in the quarter-finals of two European competitions back-to-back."
West Ham finished the group stages with a perfect record but have struggled in the Premier League this season and are currently just one point above the relegation zone.