Southampton outclassed a much-changed Arsenal side to seal a comfortable victory at the Emirates Stadium and secure an EFL Cup semi-final berth for the first time in 29 years.
Arsene Wenger made 10 changes to his team from Sunday's win over Bournemouth but those who came into the starting line-up were found wanting as Saints were good value for their 2-0 win.
The visitors, showing eight changes of their own from the weekend, eased through as Jordy Clasie's first goal for the club was followed up by a smart Ryan Bertrand finish as Claude Puel's men wrapped up the win before half-time.