Chelsea are hoping Levi Colwill and Christopher Nkunku could return from respective toe and hamstring injuries.
The Blues were without 14 players for the midweek win over Tottenham, including Thiago Silva, Enzo Fernandez and Ben Chilwell.
West Ham's Konstantinos Mavropanos could return after missing the last three matches.
Fellow defender Nayef Aguerd remains sidelined but the Hammers have no fresh injury problems.
MATCH FACTS
Head-to-head
- Chelsea have lost just one of their last 17 home league games against West Ham United (W12, D4), including winning the last three.
- However, the Hammers won the reverse fixture in August despite playing for almost 30 minutes with 10 men.