Bournemouth could hand debuts to a host of new signings, including full-backs Max Aarons and Milos Kerkez.
Midfielder Alex Scott arrives from Bristol City with a knee injury and will join Ryan Fredericks, Lloyd Kelly and Marcus Tavernier on the sidelines.
West Ham manager David Moyes has a fully fit squad to choose from.
Mexican midfielder Edson Alvarez has declared himself ready for the season opener and the £32m signing could make his debut on the south coast.
MATCH FACTS
Head-to-head
- Bournemouth have lost their past three top-flight games versus West Ham without scoring.