Everton travel to Vicarage Road having lost just once of their last two in 24 games against Watford in all competitions.
However, they have a woeful away record in the Premier League this season and have just won once in their last 21 outings on the road.
The Hornets will be hoping star man Richarlison can find some form soon, he hasn't scored in his last 17 games, a run stretching back to mid-November.
This 10th Premier League fixture between the clubs will have the 11th and 12th different managers in charge.