After a scoreless first half, Meek scored for the Huskies in the 54th minute. Moments later, Ostrem sent a blast from atop the box into the top right corner.
Goalkeeper Sam Fowler extended his Washington record with his 29th postseason save. He got a hand on Marlon Tabora's shot in the 70th minute to push it up and over the net.
Zach Riviere closed the gap for the Hoyas with a header in the 80th minute. He had a chance to tie it in the final seconds but his attempt went over the goal.