Hatcher completed 27 of 41 passes in the win. It gave him 100 completions in his first four games as a Bobcat, the most ever by a Texas State (2-2) quarterback after four games since the school moved to the FBS level in 2012.
Marcell Barbee caught six passes for 112 yards and a touchdown for the Bobcats.
Texas State outgained Houston Christian in total yardage, 479-142. The Huskies hadn't been shutout since a 76-0 defeat against Sam Houston on Nov. 15, 2014.
The Bobcats won the only previous meeting between the schools, 20-11, on Sept.