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If Ohio State loses this week, its playoff hopes are likely over.

If Michigan State loses, its playoff hopes are over. Same for Oklahoma, TCU and Baylor.

Say goodbye to at least one top-10 team this week -- if not two or three.

It will be an unforgiving Week 12, which features six games between two ranked opponents, including two matchups between top-10 teams. The loser of the Baylor-Oklahoma State game will fall out of the top 10. And if No. 9 Michigan State loses at No. 3 Ohio State, it too will lose its grasp on a top-10 spot.