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March Madness 2021: Virginia opens as 10.5-point favorites over Ohio

Your No. 4 Virginia Cavaliers will be taking on the No. 13 Ohio Bobcats next Saturday to begin their title defense in the 2021 NCAA Tournament.

Though there are still lots of unknowns, Virginia is opening as a 10.5-point favorite over the Bobcats, according to Circa Sports.

Most critically among the unknowns is which Virginia players will be available come Saturday. NCAA protocols require seven consecutive days of negative Covid-testing, and there’s no confirmation on who and how many players had tested positive at the end of last week.