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NCAA Tournament game guide: Opportunity knocks for 3-seed Utah Utes vs. Gonzaga Bulldogs

The message is straightforward, but doesn't always sink in: Anyone can lose in March. A lot of teams — and their fans — have learned that the hard way this year.

You can bet that's been drilled in the Utes, who now look good by comparison running by Fresno State, 80-69, on Thursday. Many other higher seeds weren't so lucky: The 10 double-digit seeds that made it through to the second round set a new record for double-digit seed upsets. In the Midwest region alone, there's five lower seeded-teams that advanced — most notably setting up a Syracuse (10) and Middle Tennessee State (15) match-up that determines a Sweet 16 berth.