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NFL roundup: 49ers rout Packers 37-6; Bills stymie Broncos 20-3

SANTA CLARA, Calif. • Jimmy Garoppolo threw two long touchdown passes and the San Francisco harassed Aaron Rodgers all night, leading the 49ers to a 37-8 victory over the Green Bay Packers on Sunday.

Garoppolo connected on a 42-yard touchdown strike to Deebo Samuel in the second quarter and a 61-yarder to George Kittle in the third to get San Francisco (10-1) off to a resounding start to a grueling three-game stretch.

Following the game against the first-place Packers (8-3), the Niners will travel to Baltimore (8-2) and New Orleans (9-2) the next two weeks in a stretch that will go a long way to determining whether San Francisco will be able to hold off Seattle (9-2) in a tight NFC West race.