The USC football odds for the upcoming match up with Arizona opened with Trojans as 16.5-point favorites over the Wildcats.
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The line quickly shifted a point greater at 17.5, according to VegasInsider.com.
USC is coming off of their first two game winning streak in the conference this season, having dispatched Utah and Cal to bounce back from conference losses to Stanford and Washington.
Meanwhile, Arizona looks far from the team that won the Pac-12 South a year ago. The Wildcats are 5-4 this year with all four losses coming in conference.