USC returns to Memorial Stadium for the second time in two years with an interim head coach.
In 2013, interim coach Ed Orgeron and the Trojans defeated California, 62-38.
This is season, USC is 1-1 under interim Coach Clay Helton and 4-3 overall.
California, 5-2, hasn't defeated USC since 2003.
USC announced its starting lineups.
Offense: Quarterback Cody Kessler, tailback Justin Davis, fullback Jahleel Pinner, tight end Taylor McNamara, receivers Jalen Greene and JuJu Smith-Schuster and offensive linemen Chad Wheeler, Damien Mama, Khaliel Rodgers, Viane Talamaivao and Zach Banner.
Defense: Linemen Delvon Simmons, Antwaun Woods and Greg Townsend Jr.