The England defender won't take part in Sunday's qualifier after picking up an injury in training
England manager Gareth Southgate says being forced to withdraw Joe Gomez through injury is something "you couldn't make up if you tried".
Gomez, who was involved in a bust up with Raheem Sterling last week, was brought on to a chorus of boos on Thursday at Wembley against Montenegro.
While his national team-mates quickly expressed their support for the Liverpool defender, he has since succumbed to a minor injury and been omitted from the squad to face Kosovo on Sunday, along with Jordan Henderson.