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Mexico City's Azteca stadium is more than the sum of its parts. Opened in 1966, it's been the spiritual (and actual) home of the Mexico national team and Club America ever since. Pele and Diego Maradona both lifted the World Cup in the Azteca, in 1970 and 1986 respectively.
As for the U.S. national team? Let's just say their record there puts the "dos a cero" in Columbus, Ohio, to shame: The Yanks have won just once, in a 2012 friendly, with nine defeats (aggregate score: 22-5 to Mexico) and two scoreless draws.