I have researched rosters, read preseason reports and watched film, all in preparation to decide who I think will be the most impactful U21 American players in the MLS in 2022. This isn’t a list of the most talented U21s in MLS (born in 2001 or later). It’s a list of who will have the biggest role and who will make the most of that role. This list is based on anticipated amount of minutes, system/style of play fit, the player’s talent level and their supporting cast. Injuries are something we do not hope for nor can we predict, but that will also play a massive role in what young players get an opportunity this season.