Borussia Dortmund teenager Christian Pulisic headlines Jurgen Klinsmann's squad list ahead of critical CONCACAF World Cup qualifiers against Mexico on Nov. 11 and Costa Rica four days later.
In all, Klinsmann selected 26 players, which included the returns of Bayern Munich midfielder Julian Green and Colorado Rapids midfielder Jermaine Jones to the national team setup.
The German boss also gave 18-year-old Tottenham center-back Cameron Carter-Vickers his first call.
The 18-year-old Pulisic, who became the youngest American to score an international goal in the modern era earlier this year, has been regularly counted on by Dortmund boss Thomas Tuchel this season
The Pennsylvania-born midfielder has already made eight appearances for the national team, scoring three goals.