Barcelona have ruled goalkeeper Neto out for up to eight weeks with a fractured left wrist.
The new signing underwent an operation on Tuesday after suffering the injury during training prior to the 4-0 weekend win over Napoli in Michigan.
The 30-year-old joined Barca from Valencia in June in a deal worth an initial €26 million (£23m/$30m) as Jasper Cillessen moved in the opposite direction.
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His absence leaves the La Liga champions without an experienced competitor for first-choice Marc-Andre ter Stegen ahead of Friday's season opener against Athletic Bilbao.