Tigres UANL advanced to the Concacaf Champions League final, despite a 3-2 second-leg defeat at Santos Laguna.
Santos fought back with three unanswered goals but first-half strikes from Enner Valencia and Julian Quinones gave Tigres a 5-3 aggregate victory.
Through to their third final in four seasons, Tigres – who have never won the competition – will face either Monterrey or Sporting Kansas City in the decider.
Tigres were in a commanding position heading into Wednesday's return fixture thanks to last week's 3-0 win on home soil – inspired by Valencia's brace.