Alexis Sanchez suffered an ankle injury during Chile's win over Ecuador at the Copa America, coach Reinaldo Rueda confirmed.
Sanchez scored a 51st-minute winner to send the two-time defending champions into the quarter-finals courtesy of a 2-1 victory on Friday.
Chile opened the scoring through Jose Pedro Fuenzalida, who fired in the eighth minute to give the defending Copa America champions the lead.
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Ecuador fired back 18 minutes later as Enner Valencia tucked home from the spot, but it was Sanchez that proved the match-winner by scoring just six minutes after the halftime break.