A goal in either half saw Asante Kotoko beat Etoile du Sahel 2-0 in the Caf Champions League in Kumasi on Sunday.
Augustine Okrah's early strike and Richard Arthur's second-half effort ensured a home win for the Porcupine Warriors in the first round first leg fixture at Baba Yara Sports Stadium.
Their first triumph over the Tunisians in five encounters, the Ghanaians must hold their own in the return game on September 27 to book a place in the group stage.
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The main talking point of Kotoko's team news was coach Kjetil Zachariassen's decision to hand starting berths to Jordan Opoku and Okrah who both have had to delay their debuts in this season's championship due to paperwork issues.