Tulane will play a third non-conference game against a team that played in the 2018 NCAA tournament.
South Dakota State, a 28-game winner last season, will be the opening-round opponent for the Green Wave at the eight-team Gulf Coast Showcase when the tournament tips Nov. 19 in Estero, Florida.
South Dakota State won the Summit League tournament last season to earn the NCAA bid.
Other schools on the Tulane side of the bracket for the Thanksgiving-week tournament are UC Irvine, UT-San Antonio. On the opposite side are Louisiana-Lafayette, Colorado State, Toledo and Florida Gulf Coast.
Tulane will play two home games against 2018 NCAA qualifiers.