The £30 million signing has often looked out of place in Mauricio Pochettino’s side with his lack of guile when in possession of the ball.
Sissoko produced another lacklustre performance for the Lilywhites on Sunday evening as his side slumped to a disappointing draw away to Southampton.
Spurs missed their chance to move into the top four of the Premier League and many fans vented their frustrations towards a certain someone, who struggled on the south coast.
talkSPORT takes a look at the best reactions from fans online…