Tottenham boss Antonio Conte admitted his side face a tough task to overturn a two-goal deficit against Chelsea and reach the Carabao Cup final.
The second leg of the semi-final takes place on Wednesday after Chelsea won 2-0 at Stamford Bridge, with a goal from Kai Havertz and Ben Davies' own goal.
Chelsea will wait to see if defender Thiago Silva and midfielder N'Golo Kante have recovered from Covid-19.
Tottenham will be without Son Heung-min because of a muscle problem.
The forward picked up the injury during last week's first leg and will not play again before the international break, which starts on 24 January.