The 22-year-old, who is the son of Atletico Madrid manager Diego Simeone, has scored 13 times in Serie A this season.
And now, according to Tuttosport, the Argentine is on the radar of several clubs ahead of the summer transfer window.
It is reported that five sides want to sign Simeone, with Tottenham hoping to lure him to England.
Spurs could well be in the market for a new striker this summer if Fernando Llorente leaves.
The Spaniard joined from Swansea last year, but he has not featured regularly and will have only one year left on his contract at the end of the season.