Tottenham are without South Korea forward Son Heung-min, who is doubtful for the World Cup after fracturing his eye socket against Marseille.
Liverpool are missing James Milner, who is observing concussion protocol after being forced off against Napoli.
Midfielder Jordan Henderson missed that game with a minor issue but is back in contention.
CHRIS SUTTON'S PREDICTION
Son Heung-min's injury is especially bad timing for Tottenham at the moment with two other attacking players, Richarlison and Dejan Kulusevski, already out.
The only bit of good news for Spurs fans is that I am backing Liverpool to win, and I have been wrong about pretty much every Liverpool result this season.