Tottenham will be without left-back Danny Rose and midfielder Erik Lamela for Thursday's Europa League last-32 second-leg tie against Gent at Wembley.
Rose has missed four matches after injuring his knee in January's 0-0 draw with Sunderland, while Lamela has been absent since October with a hip injury.
The game starts at 20:05 GMT and Spurs trail 1-0 after the first leg, but have never lost to a Belgian team at home.
Spurs boss Mauricio Pochettino said the game was "another final at Wembley".
He added: "We need to use all our energy to find a way to the next round.