Tottenham Hotspur are taking a full-strength squad to North Macedonia for Thursday's Europa League third qualifying round tie with Shkendija.
The winners of that game host Rostov or Maccabi Haifa next week for a place in the group stages.
Spurs' EFL Cup game on Tuesday was called off as Leyton Orient players tested positive for coronavirus.
"The team that was supposed to play last night is different to the team tomorrow," boss Jose Mourinho said.
"The main reason is that we played last Sunday at Southampton and one thing is Sunday, Tuesday and another is Sunday, Thursday.