Tottenham sporting director Fabio Paratici held talks with AC Milan on Thursday regarding defender Japhet Tanganga's loan move.
Milan have also asked about prospective deals for Tanguy Ndombele and Sergio Reguilon, who are also surplus to requirements at Spurs.
Paratici and Milan also discussed the possibility of Tottenham midfielder Pape Matar Sarr going on loan to the Italian champions.
The 19-year old Senegal international spent last season loan at previous club Metz.
Tanganga is currently the subject of much interest after Antonio Conte and Spurs opened the possibility of him leaving on loan this summer.