Morecambe manager Stephen Robinson will miss his side's FA Cup third round tie against Tottenham on Sunday after testing positive for Covid-19.
Morecambe's assistant manager Diarmuid O'Carroll will take charge of the team against the Premier League side.
The Shrimps, who won at non-league Buxton in round two, are 19th in League One, a point above the relegation zone.
Tottenham head into the tie looking to bounce back from their 2-0 Carabao Cup semi-final first-leg defeat at Chelsea on Wednesday.
Meanwhile, Bristol Rovers manager Joey Barton will also miss his side's third round tie with Peterborough after a positive Covid test.