Mauricio Pochettino accepts more of Tottenham's star players may look to follow Kyle Walker's example by leaving the club to win trophies.
But Pochettino stressed Spurs sanction sales on their own terms, with Walker only allowed to join Manchester City for a hefty £52million last summer.
City are 11 points clear at the top of the table ahead of Saturday's showdown with Tottenham and Walker has started all but two of their league games so far. He has also more than doubled his wages at his new club.
Tottenham, meanwhile, have made great strides in the last three years but are yet to win any silverware under Pochetttino, who admits some of his players may not want to wait for success.