Manchester City hope that Jack Grealish will be able to return to their squad following a two-match absence with a shin problem.
Tottenham head coach Antonio Conte is boosted by the availability of Eric Dier, who missed the last three games with a thigh injury.
Defender Japhet Tanganga is still out, while Oliver Skipp is also again expected to be absent.
LAWRO'S PREDICTION
Tottenham beat Manchester City on the opening weekend of the season, but there are plenty of reasons it has not turned into the campaign that Spurs fans would have hoped for on the back of that result.