Luton Town will assess defender Amari'i Bell, who limped off after just 20 minutes of the midweek defeat by Burnley with a hamstring problem.
Midfielder Ross Barkley has returned to training after his own hamstring issue and could feature.
Tottenham forward Manor Solomon has undergone surgery after suffering a knee injury in training.
Brennan Johnson remains sidelined with the hamstring problem which caused him to miss last week's win over Liverpool.
MATCH FACTS
Head-to-head
- These two sides are meeting for the first time since March 1992.
- Tottenham are unbeaten in nine league matches against Luton (W5, D4), with the Hatters last winning against Spurs in November 1987.