Tottenham Hotspur boss Jose Mourinho says he trusts England manager Gareth Southgate and Wales counterpart Ryan Giggs to protect his players.
Spurs will play their eighth game since 13 September when they travel to Manchester United on Sunday.
The Old Trafford match falls prior to an international break when countries play three games in a week.
"You know, I believe that Gareth and [assistant] Steve [Holland], they care about the players," said Mourinho.
Mourinho worked with Southgate's assistant Holland at Chelsea but says he will not request that England captain Kane is rested by his country and is confident the international coaching teams will look after his players' welfare.