Frankfurt achieved a key victory as they kept alive their hopes of emerging from Group D in the Champions League.
With all four teams separated by merely two points, all sides knew a victory on the penultimate matchday would provide them an excellent chance of emerging out of the group stage's tightest pool.
Goals from Daichi Kamada and Randal Kolo Muani gave the German outfit, who are in the competition by virtue of winning the Europa League in May, all three points.
The result means that Marseille will have to beat Tottenham next week in France to stand any chance of reaching the last 16.