If the clash between these two sides at Stamford Bridge is anything to go by, we can expect goals, controversy, mass brawls and managers seeing red - in more ways than one.
It was back in August when Harry Kane's stoppage-time header salvaged a 2-2 draw for Tottenham against Chelsea - in a game marred by ugly scenes at full-time.
Former Chelsea managers Thomas Tuchel and Antonio Conte were both handed red cards after squaring up to one another and sparking a melee on the pitch. An incandescent Tuchel blamed the Spurs boss for instigating the heated row by not looking into his eyes as they shook hands.