Ben Davies has withdrawn from the Wales squad for Euro 2024 qualifiers against Croatia and Latvia because of injury.
Davies was substituted during Tottenham Hotspur's Premier League draw at Southampton last Saturday with a suspected hamstring problem.
Stoke defender Morgan Fox has been called in to the squad, along with additional goalkeeper Tom King.
Wales face Croatia in Split on Saturday before taking on Latvia in Cardiff three days later.
Defender Davies, 29, was named vice-captain by Robert Page when the Wales squad was announced earlier this month.
His absence is a significant blow as Wales prepare for their first action since last year's World Cup.