Ben Davies has withdrawn from the Wales squad for Euro 2024 qualifiers against Croatia and Latvia because of injury.
Goalkeeper Wayne Hennessey has also withdrawn from the squad and returns to Nottingham Forest, while Brennan Johnson requires further assessment.
Defender Morgan Fox, goalkeeper Tom King, and forwards Liam Cullen and Mark Harris come into the squad.
Wales face Croatia in Split on Saturday before taking on Latvia in Cardiff three days later.
Davies, 29, was substituted during Tottenham Hotspur's Premier League draw at Southampton last Saturday with a suspected hamstring problem.
The defender was named vice-captain by Robert Page when the Wales squad was announced earlier this month.