Hugo Lloris and David De Gea in goal at each end, Toby Alderweireld and Jan Vertonghen up against Zlatan Ibrahimovic, Paul Pogba and Dele Alli in midfield, the list could go on...
Mauricio Pochettino isn't looking at names or duels though. "For me, it's Manchester United v Tottenham, two big clubs, two teams that want success in England and in Europe, that’s most important," he said. "The duelling on the pitch is 11 v 11 from the beginning and then we’ll see."
Below: Mauricio previews the game on Spurs TV
How do the players feel ahead of this game?