SEATTLE, WA - DECEMBER 11: Dr. Jesse Erasmus dilutes a serum samples collected from animals that received a replicon, or replicating, RNA vaccine being developed to combat Covid-19 (SARS-CoV-2), at a microbiology lab at the University of Washington School of Medicine on December 11, 2020 in Seattle, Washington. Scientists are hoping this nucleic acid vaccine will only need one dose to be effective against the coronavirus and that it won't need to be stored in a deep freeze. This replicon RNA vaccine has been tested on mice and macaque monkeys and is in early stage clinical development with HDT Bio who will be leading the clinical trials of it in the United States.